Inquiry Basket
FAM alkyne, 5-isomer | 510758-19-7
| Catalog Number | R02-0026 |
| Category | Fluorescein FAM |
| Molecular Formula | C25H15O6N |
| Molecular Weight | 413.38 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R02-0026 | -- | $-- |
- Worldwide Delivery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
FAM (fluorescein) alkyne for copper-catalyzed Click chemistry, high purity (97+%) 5-isomer. The compound possesses significant aqueous solubility.
Chemical Information |
|
|---|---|
| Synonyms | 5-FAM-Alkyne; 3',6'-dihydroxy-3-oxo-N-(prop-2-yn-1-yl)-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxamide; 3',6'-dihydroxy-3-oxo-N-prop-2-ynylspiro[2-benzofuran-1,9'-xanthene]-5-carboxamide; FAM alkyne; 5-FAM alkyne; 5-carboxyfluorescein, propargylamide |
| Purity | NMR 1H, HPLC-MS (95%) |
| IUPAC Name | 3',6'-dihydroxy-3-oxo-N-prop-2-ynylspiro[2-benzofuran-1,9'-xanthene]-5-carboxamide |
| Canonical SMILES | C#CCNC(=O)C1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O |
| InChI | InChI=1S/C24H15NO6/c1-2-9-25-22(28)13-3-6-17-16(10-13)23(29)31-24(17)18-7-4-14(26)11-20(18)30-21-12-15(27)5-8-19(21)24/h1,3-8,10-12,26-27H,9H2,(H,25,28) |
| InChI Key | UNBAJBIGCBVWJU-UHFFFAOYSA-N |
| Solubility | good in aqueous buffers (pH > 8), alcohols, DMSO, DMF |
| Appearance | yellow solid |
- Product Specification
| ε, L⋅mol-1⋅cm-1 | 80000 |
| Fluorescence Quantum Yield | 0.93 |
| Excitation | 490 |
| Emission | 513 |
| Storage | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
| Signal | Warning |
| GHS Hazard Statements | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
| Precautionary Statement Codes | P264, P270, P301+P317, P330, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Computed Properties | |
|---|---|
| XLogP3 | 2.8 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 413.08993720 g/mol |
| Monoisotopic Mass | 413.08993720 g/mol |
| Topological Polar Surface Area | 105Ų |
| Heavy Atom Count | 31 |
| Formal Charge | 0 |
| Complexity | 762 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2019030284-A1 | NOVEL TARGETED CYTOTOXIC RATJADONE DERIVATIVES AND CONJUGATES THEREOF | 2017-08-09 |
| US-2020239426-A1 | Targeted cytotoxic ratjadone derivatives and conjugates thereof | 2017-08-09 |
| US-11236059-B2 | Targeted cytotoxic ratjadone derivatives and conjugates thereof | 2017-08-09 |
| WO-2018151810-A1 | Defining rna-small molecule affinity landscapes enables design of a small molecular inhibitor of an oncogenic non-coding rna | 2017-02-17 |
| EP-3030548-A1 | Transcriptome-wide design of selective, bioactive small molecules targeting rna | 2013-08-09 |
Applications of Fluorescent Probes & Dyes
Get More Product Details?
