2-(1-Naphthyl)-5-phenyloxazole

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2-(1-Naphthyl)-5-phenyloxazole

2-(1-Naphthyl)-5-phenyloxazole | 846-63-9

Catalog Number A17-0111
Category Laser Dyes
Molecular Formula C19H13NO
Molecular Weight 271.319
Catalog Number Size Price Quantity
A17-0111 -- $--

Product Introduction

2-(1-Naphthyl)-5-phenyloxazole is a biochemical for proteomics research.

Chemical Information

Synonyms 2-(1-naphthalenyl)-5-phenyl-oxazole; alpha-NPO; a-NPO
IUPAC Name 2-naphthalen-1-yl-5-phenyl-1,3-oxazole
Canonical SMILES C1=CC=C(C=C1)C2=CN=C(O2)C3=CC=CC4=CC=CC=C43
InChI InChI=1S/C19H13NO/c1-2-8-15(9-3-1)18-13-20-19(21-18)17-12-6-10-14-7-4-5-11-16(14)17/h1-13H
InChI Key WWVFJJKBBZXWFV-UHFFFAOYSA-N
  • Application

2-(1-Naphthyl)-5-phenyloxazole, commonly known as PPO, is a versatile organic compound widely utilized as a scintillator across diverse fields. Here are four key applications of 2-(1-Naphthyl)-5-phenyloxazole:

Radiation Detection: Serving as a luminescent substance, PPO plays a pivotal role in radiation detectors by efficiently converting ionizing radiation into visible light. This unique property renders it indispensable in a myriad of settings, including nuclear physics experiments, medical imaging, and environmental surveillance. With its remarkable sensitivity and rapid response time, PPO facilitates precise and reliable radiation detection and quantification.

Bioluminescence Assays: Within the realm of biological research, PPO finds application in bioluminescence assays aimed at assessing ATP levels, enzymatic activities, and cellular functions. When combined synergistically with other substances, PPO enables the visualization of light emanating from bioluminescent processes. This application is fundamental in expedited screening processes and diagnostic analyses crucial for drug discovery endeavors and clinical investigations.

Liquid Scintillation Counting: Integral to liquid scintillation cocktails, PPO aids in the quantification of beta-emitting radionuclides present in biological and environmental samples. Its exceptional ability to effectively transfer energy to scintillators is key to ensuring precise and sensitive measurements. Widely employed in radiolabeling studies, environmental monitoring initiatives, and biological tracer experiments, this technique epitomizes accuracy and reliability in radiation quantification.

Fluorescence Spectroscopy: In the realm of spectroscopy, PPO serves as a fluorescent probe essential for studying molecular interactions and dynamics. With its intense fluorescence emission, PPO facilitates the examination of biomolecular behavior and concentration levels. Researchers harness the power of PPO in various fluorescence-based methodologies to unravel the structural intricacies and functional attributes of biological systems, shedding light on their complexities.

Computed Properties

Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 2
Exact Mass 271.099714038 g/mol
Monoisotopic Mass 271.099714038 g/mol
Topological Polar Surface Area 26Ų
Heavy Atom Count 21
Formal Charge 0
Complexity 339
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Literatures

PMIDPublication DateTitleJournal
21609030 2011-06-15 Preparation of polymer-coated, scintillating ion-exchange resins for monitoring of 99Tc in groundwater Analytical chemistry
16579605 2006-04-01 Evaluation of flow cell detector configurations combining simultaneous preconcentration and scintillation detection for monitoring of pertechnetate in aqueous media Analytical chemistry

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