N-(m-PEG4)-N'-(PEG4-acid)-Cy5

What We Offer

N-(m-PEG4)-N'-(PEG4-acid)-Cy5

N-(m-PEG4)-N'-(PEG4-acid)-Cy5 | 2107273-32-3

Catalog Number A17-0174
Category Cyanine5
Molecular Formula C45H65ClN2O10
Molecular Weight 829.5
Catalog Number Size Price Quantity
A17-0174 -- $--

Product Introduction

N-(m-PEG4)-N'-(PEG4-acid)-Cy5 is a near infrared (NIR) fluorescent Cy 5 labeled PEG linker containing free terminal carboxyl acid. Terminal carboxylic acid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydophilic PEG spacer increases solubility in aqueous media. Cy5 labeled PEG linker can be easily traced from its blue color and strong fluorescence.

Chemical Information

Synonyms 2-(5-(1-(14-Carboxy-3,6,9,12-tetraoxatetradecyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3,3-dimethyl-1-(2,5,8,11-tetraoxatridecan-13-yl)-3H-indol-1-ium chloride
Purity 98%
IUPAC Name 3-[2-[2-[2-[2-[(2E)-2-[(2E,4E)-5-[1-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl]-3,3-dimethylindol-1-ium-2-yl]penta-2,4-dienylidene]-3,3-dimethylindol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid;chloride
Canonical SMILES CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=C3C(C4=CC=CC=C4N3CCOCCOCCOCCOCCC(=O)O)(C)C)CCOCCOCCOCCOC)C.[Cl-]
InChI InChI=1S/C45H64N2O10.ClH/c1-44(2)37-13-9-11-15-39(37)46(20-23-52-28-31-56-34-33-54-26-25-50-5)41(44)17-7-6-8-18-42-45(3,4)38-14-10-12-16-40(38)47(42)21-24-53-29-32-57-36-35-55-30-27-51-22-19-43(48)49;/h6-18H,19-36H2,1-5H3;1H
InChI Key VGWYWHBAFATVCR-UHFFFAOYSA-N
Solubility Water, DMSO, DMF, DCM
  • Product Specification
Excitation 649
Emission 667
Storage -20 °C

Computed Properties

Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 12
Rotatable Bond Count 30
Exact Mass 828.4327740 g/mol
Monoisotopic Mass 828.4327740 g/mol
Topological Polar Surface Area 117Ų
Heavy Atom Count 58
Formal Charge 0
Complexity 1280
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 3
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

Patents

Publication NumberTitlePriority Date
US-2017197916-A1 Functionalized pegylated cyanine compounds, pharmaceutical compositions, and methods of use thereof 2016-01-08
US-9862682-B2 Functionalized pegylated cyanine compounds, pharmaceutical compositions, and methods of use thereof 2016-01-08
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