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4-Methylumbelliferyl Palmitate | 17695-48-6
| Catalog Number | A18-0102 |
| Category | Fluorescent Enzyme Substrates |
| Molecular Formula | C26H38O4 |
| Molecular Weight | 414.6 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A18-0102 | -- | $-- |
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Product Introduction
4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL). 4-MUP is cleaved by LAL to release the fluorescent moiety 4-MU.
Chemical Information |
|
|---|---|
| Synonyms | 4-MUP; 4-MU Palmitate; Palmitoyl 4-Methylumbelliferone; hexadecanoic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester |
| Purity | ≥98% |
| IUPAC Name | (4-methyl-2-oxochromen-7-yl) hexadecanoate |
| Canonical SMILES | CCCCCCCCCCCCCCCC(=O)OC1=CC2=C(C=C1)C(=CC(=O)O2)C |
| InChI | InChI=1S/C26H38O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25(27)29-22-17-18-23-21(2)19-26(28)30-24(23)20-22/h17-20H,3-16H2,1-2H3 |
| InChI Key | QKQVFFACWLFRRX-UHFFFAOYSA-N |
| Appearance | White to Off-white Solid |
| Melting Point | 75-77°C |
- Product Specification
| Storage | Store at -20°C |
| Signal | Warning |
| GHS Hazard Statements | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Computed Properties | |
|---|---|
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 16 |
| Exact Mass | 414.27700969 g/mol |
| Monoisotopic Mass | 414.27700969 g/mol |
| Topological Polar Surface Area | 52.6Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 539 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22483793 | 2012-08-16 | A new method for the measurement of lysosomal acid lipase in dried blood spots using the inhibitor Lalistat 2 | Clinica chimica acta; international journal of clinical chemistry |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022263950-A1 | Biological indicator with adjusted resistance characteristics | 2021-06-16 |
| WO-2022164860-A1 | Materials and methods for the treatment of lysosomal acid lipase deficiency (lal-d) | 2021-01-27 |
| WO-2022034498-A1 | Moving-front sterilization monitoring devices | 2020-08-12 |
| WO-2021214595-A1 | Biological indicator with test microorganisms enveloped by wax composition | 2020-04-22 |
| WO-2021186267-A1 | Immobilized ph indicator for biological indicator growth indication | 2020-03-17 |
Applications of Fluorescent Probes & Dyes
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